Slc14a2/Ut-A (AA 501-600) anticorps

N° du produit ABIN1386585

Cet anticorps anti- est un anticorps Lapin Polyclonal détectant dans ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p) et WB. Adapté pour Humain.

Aperçu rapide pour Slc14a2/Ut-A (AA 501-600) anticorps (ABIN1386585)

Antigène: Slc14a2/Ut-A

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Détail du produit

Épitope: AA 501-600

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SLC14A2/UT-A

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Slc14a2/Ut-A

Sujet:

Synonyms: HUT2, kidney, MGC119566, MGC119567, Slc14a2, Solute carrier family 14 urea transporter, member 2, Solute carrier family 14 member 2, Urea transporter 2, Urea transporter, Urea transporter, kidney, UT-A2, UT2, UT2_HUMAN, UTA, UTR, FLJ16167, hUT-A6.

Background: Water balance is tightly regulated in the kidneys. Through urinary concentration mechanisms, the kidney prevents the unnecessary excrement of water, thereby protecting the body from dehydration. UT-A (Urea transporter, kidney), also known as SLC14A2 and HUT2, is a 920 amino acid multi-pass membrane protein that functions as a specialized low-affinity vasopressin-regulated urea-transporter. Expressed in the inner medulla of the kidney and localized to the apical membrane, UT-A mediates rapid transepithelial urea transport across the inner medullary collecting duct. There are two isoforms of UT-A that are produced as a result of alternative splicing events. Isoform 1 interacts with Snapin, a SNARE-associated protein, which is thought to help in its recruitment to the plasma membrane. Interestingly, isoform 1 expression is induced by low protein in the diet, whereas isoform 2 expression is induced by dehydration.

ID gène: 8170